1. Is it possible to participate in ADICOL project ?
2. Are there any research programms planned in other (non-European) countries ?
3. Is there already a time frame to comercial deployment ?
4. When will a product be available ?
5. How is the ADICOL project progressing ?
6. Which glucose sensor technologies are investigated in the project ?
7. What is the role of the expert software ?
Answer: ADICOL is a 3 year research project (lasting until the end of 2002) and no volunteer participation is possible during this period. Ethic concerns and safety regulations limit human trials to small numbers in selected clinics only.
Answer: ADICOL is an European-based project which in part is public funded. The research program is confined to the countries of origin of the project partners. In other countries e.g. the United States no tests will be conducted within the ADICOL project.
Answer: The goal of the project is to develop a device which will measure blood glucose continuously for up to 3 days. The data will be used on-line to optimise actual insulin requirement. This part of the project and the necessary clinical trials are performed under control of physicians. If these trials are successful then product development should start at the end of the project in 2002.
Answer: The goal of the research project ADICOL is the proof of the concept. Existing products such as an extracorporeal insulin pump will be used to generate a control loop. Successful tests on a limited number of patients under controlled conditions will reveal if the concept holds for a subsequent product development phase starting after 2002.
Answer: The project is running since January 1, 2000 and substantial progresses in all areas of work have been made:
- development of glucose sensors and glucose monitoring system
- remote control of modern insulin infusion systems
- adaptation of control algorithms to pump therapy
- communication between personal equipment devices
- clinical trials to assess the progress
- thick film technology (screen print)
- thin film technology (silicon based)
Both of them offer different advantages. At present the tests are being carried out on the long-term properties for continuous use over days without the need for re-calibration.
Answer: The "expert software" plays the important role of "translating" the glucose sensor readings into information on how to cover insulin requirements. Computer programmes are used to control the insulin infusion. We are testing the "expert software" to cover for actual insulin requirements and as well to optimise the long term CSII.